Cardiometrix

Heart failure is a significant global health challenge, affecting millions of people worldwide. It arises from various causes, including ischemic heart disease, hypertension, valvular abnormalities, and cardiomyopathies. The primary issue in heart failure is the heart's inability to efficiently pump blood, leading to debilitating symptoms and high mortality rates. Traditional management has focused on alleviating symptoms and enhancing cardiac function through medications and device-based interventions.  Despite the progress in conventional treatments, heart failure continues to be a clinical challenge due to complex underlying mechanisms such as neurohormonal activation, cardiac fibrosis, and cellular remodeling. Several emerging therapies could address these challenges.     Gene therapy , including gene-editing techniques like CRISPR-Cas9, for correcting genetic mutations contributing to heart failure, offers a promising avenue for addressing the root causes of this condition.  

Doctors have been listening to the sounds our bodies make for centuries. Before the invention of stethoscopes, they simply put their ears to their patients' chests or abdomens, to listen to the sounds produced by our body's internal workings. Today, the practice of auscultation, using a stethoscope to examine a patient, has evolved into a sophisticated diagnostic tool that provides valuable insights into various aspects of our health: lungs, heart, bowel, vocal cords, joints, arterial conditions, sleep quality and more. Moreover, by amalgamating biomarkers and clinical data with a myriad of acoustic cues like sneezes, breath patterns, speech, throat clearings, wheezes, and more, the healthcare decision-making process stands poised for remarkable enhancement.  Auscultation is a valuable diagnostic tool because it is safe and noninvasive. Doctors place their stethoscopes at various positions on the chest to listen to different heart valves. The sounds they hear include the closur

Traditionally, heart rate (HR) monitoring requires the use of wearable devices, which can be inconvenient and uncomfortable, particularly during sleep and meditation.  A study published yesterday in Scientific Reports introduces a non-invasive approach to noncontact HR detection, utilizing Soli radar technology (millimeter wave radar) embedded in a portable device, in this case, the Google Nest Hub. The Soli radar chip featured in this study offers a compact dimension and can be easily integrated into various devices, making it a promising alternative to traditional HR monitoring methods. Unlike existing approaches in the literature that rely on high-gain antennas and facing the user's chest or back, this Soli-based approach overcomes these limitations, making it suitable for sleep and meditation tracking applications. Advanced signal processing (SP) and machine learning (ML) techniques achieve impressive accuracy levels on two distinct datasets: a sleep dataset comprising data fr

A novel inexpensive diagnostic methodology promises to enhance our understanding of vascular elasticity. This innovative approach leverages the patient's heart and pulse rhythms to assess the flexibility of blood vessels.  The elasticity of blood vessels, the ability of their walls to stretch and contract, plays a pivotal role in our cardiovascular health. When blood vessel walls become stiffer, individuals become more sensitive to fluctuations in blood pressure, making them more vulnerable to serious conditions like atherosclerosis and heart disease. The scientists at Samara University have proposed a more straightforward method for evaluating vascular elasticity. This methodology is based on the analysis of differences between the patient's heart and pulse rhythms. According to Dr. Alexander Fedotov, an associate professor at the Department of Laser and Biotechnical Systems at Samara University, "Periodic fluctuations in arterial blood pressure, known as Mayer waves, can

The management of blood pressure is an integral part of maintaining cardiovascular health. Hypertension, or high blood pressure, places the cardiovascular system under persistent stress, leading to an array of complications such as heart disease, stroke, and even kidney disease. It's a silent adversary, often showing no immediate symptoms, yet it can have serious long-term effects on the body's overall health. Proactive measures to manage and maintain healthy blood pressure levels, including regular exercise, dietary changes, and routine check-ups, play a critical role in preserving cardiovascular health and promoting overall wellbeing. The landscape of exercise and fitness has been dynamic and intriguing, with different modes of training showing varying impacts on cardiovascular health. A recent large-scale review, which analyzed 270 randomized controlled trials involving 15,827 participants, has thrown a spotlight on a seemingly underrated type of exercise: isometric exercise

A study published in the peer-reviewed journal "Nature" found that artificial intelligence (AI) is better at assessing heart function than sonographers. The study was conducted by investigators at the Smidt Heart Institute and the Division of Artificial Intelligence in Medicine at Cedars-Sinai and was a first-of-its-kind, blinded, randomized clinical trial of AI in cardiology. Cardiologists more frequently agreed with the initial assessment made by AI and made corrections to only 16.8% of the AI initial assessments. Cardiologists made corrections to 27.2% of the sonographers' initial assessments, and the physicians were unable to distinguish between AI and sonographer assessments. AI also saved cardiologists and sonographers time. The hope is to save clinicians time and minimize the more tedious parts of the cardiac imaging workflow. However, the cardiologist remains the final expert adjudicator of the AI model output. Regulatory approvals are now needed for such tools to